| Casdin Capital, LLC | 88,783,856 | $73.0m | 3.7% |
| VIKING GLOBAL INVESTORS LP | 58,651,170 | $48.3m | 0.1% |
| MAK CAPITAL ONE LLC | 28,813,904 | $23.7m | 3.3% |
| Long Focus Capital Management, LLC | 23,500,000 | $19.3m | 0.5% |
| VANGUARD CAPITAL MANAGEMENT LLC | 12,252,998 | $10.1m | 0.0% |
| BlackRock, Inc. | 8,254,443 | $6.8m | 0.0% |
| Hollow Brook Wealth Management LLC | 5,503,381 | $4.5m | 0.9% |
| NEUBERGER BERMAN GROUP LLC | 4,958,620 | $4.0m | 0.0% |
| Qube Research & Technologies Ltd | 4,820,463 | $4.0m | 0.0% |
| ROYCE & ASSOCIATES LP | 4,525,333 | $3.7m | 0.0% |
| GEODE CAPITAL MANAGEMENT, LLC | 3,896,574 | $3.2m | 0.0% |
| Tikvah Management LLC | 3,551,058 | $2.9m | 0.9% |
| MILLENNIUM MANAGEMENT LLC | 3,512,665 | $2.9m | 0.0% |
| MORGAN STANLEY | 2,831,668 | $2.3m | 0.0% |
| D. E. Shaw & Co., Inc. | 2,818,026 | $2.3m | 0.0% |
| JANE STREET GROUP, LLC | 2,514,299 | $2.1m | 0.0% |
| Peapod Lane Capital LLC | 2,411,474 | $2.0m | 1.3% |
| CITADEL ADVISORS LLC | 2,348,570 | $1.9m | 0.0% |
| Mink Brook Asset Management LLC | 2,190,973 | $1.8m | 0.8% |
| Sone Capital Management, LLC | 2,133,631 | $1.8m | 0.1% |
| ARROWSTREET CAPITAL, LIMITED PARTNERSHIP | 1,991,426 | $1.6m | 0.0% |
| VANGUARD FIDUCIARY TRUST CO | 1,889,846 | $1.6m | 0.0% |
| CHARLES SCHWAB INVESTMENT MANAGEMENT INC | 1,759,038 | $1.4m | 0.0% |
| JACOBS LEVY EQUITY MANAGEMENT, INC | 1,633,112 | $1.3m | 0.0% |
| STATE STREET CORP | 1,542,478 | $1.3m | 0.0% |