| VIKING GLOBAL INVESTORS LP | 29,993,708 | $643.4m | 1.8% |
| BlackRock, Inc. | 15,139,159 | $324.7m | 0.0% |
| VANGUARD CAPITAL MANAGEMENT LLC | 6,403,587 | $137.4m | 0.0% |
| WELLINGTON MANAGEMENT GROUP LLP | 5,911,366 | $126.8m | 0.0% |
| VANGUARD PORTFOLIO MANAGEMENT LLC | 5,476,231 | $117.5m | 0.0% |
| D. E. Shaw & Co., Inc. | 4,625,859 | $99.2m | 0.0% |
| WESTFIELD CAPITAL MANAGEMENT CO LP | 4,267,645 | $91.5m | 0.3% |
| GEODE CAPITAL MANAGEMENT, LLC | 3,641,837 | $78.1m | 0.0% |
| STATE STREET CORP | 3,458,388 | $74.2m | 0.0% |
| Invesco Ltd. | 3,094,011 | $66.4m | 0.0% |
| GOLDMAN SACHS GROUP INC | 2,984,227 | $64.0m | 0.0% |
| PRICE T ROWE ASSOCIATES INC /MD/ | 2,665,308 | $57.2m | 0.0% |
| Driehaus Capital Management LLC | 2,527,703 | $54.2m | 0.3% |
| ARROWSTREET CAPITAL, LIMITED PARTNERSHIP | 2,524,620 | $54.2m | 0.0% |
| LORD, ABBETT & CO. LLC | 2,474,814 | $53.1m | 0.2% |
| Nuveen, LLC | 2,366,155 | $50.8m | 0.0% |
| BNP PARIBAS ASSET MANAGEMENT Holding S.A. | 2,182,326 | $46.8m | 0.0% |
| FRED ALGER MANAGEMENT, LLC | 2,092,284 | $44.9m | 0.1% |
| ARK Investment Management LLC | 2,090,306 | $44.8m | 0.3% |
| NOMURA ASSET MANAGEMENT INTERNATIONAL INC. | 1,889,188 | $40.5m | 0.1% |
| Aristotle Atlantic Partners, LLC | 1,838,513 | $39.4m | 1.6% |
| T. Rowe Price Investment Management, Inc. | 1,779,651 | $38.2m | 0.0% |
| BANK OF AMERICA CORP /DE/ | 1,730,044 | $37.1m | 0.0% |
| JANE STREET GROUP, LLC | 1,590,513 | $34.1m | 0.0% |
| NORTHERN TRUST CORP | 1,507,351 | $32.3m | 0.0% |