| BAILLIE GIFFORD & CO | 56,358,374 | $1.8bn | 1.7% |
| PRICE T ROWE ASSOCIATES INC /MD/ | 48,692,589 | $1.6bn | 0.2% |
| FMR LLC | 26,406,588 | $856.4m | 0.0% |
| BlackRock, Inc. | 23,805,185 | $772.0m | 0.0% |
| VANGUARD PORTFOLIO MANAGEMENT LLC | 17,724,063 | $574.8m | 0.0% |
| VANGUARD CAPITAL MANAGEMENT LLC | 15,491,321 | $502.4m | 0.0% |
| MORGAN STANLEY | 12,348,309 | $400.5m | 0.0% |
| SANDS CAPITAL MANAGEMENT, LLC | 11,348,732 | $368.0m | 1.4% |
| GOLDMAN SACHS GROUP INC | 10,121,320 | $328.2m | 0.0% |
| WELLINGTON MANAGEMENT GROUP LLP | 9,327,606 | $302.5m | 0.1% |
| STATE STREET CORP | 7,981,248 | $258.8m | 0.0% |
| BAMCO INC /NY/ | 7,881,752 | $255.6m | 0.4% |
| BROWN ADVISORY INC | 7,109,824 | $230.6m | 0.4% |
| GEODE CAPITAL MANAGEMENT, LLC | 6,811,232 | $220.3m | 0.0% |
| WESTFIELD CAPITAL MANAGEMENT CO LP | 5,836,459 | $189.3m | 0.6% |
| a16z Perennial Management, L.P. | 5,344,484 | $173.3m | 14.0% |
| UBS Group AG | 4,556,406 | $147.8m | 0.0% |
| Jordan Park Trust Co LLC | 4,112,232 | $133.4m | 93.0% |
| CHARLES SCHWAB INVESTMENT MANAGEMENT INC | 3,657,279 | $118.6m | 0.0% |
| NORDEA INVESTMENT MANAGEMENT AB | 3,183,452 | $101.3m | 0.1% |
| Spyglass Capital Management LLC | 3,085,655 | $100.1m | 5.4% |
| Balyasny Asset Management L.P. | 3,083,647 | $100.0m | 0.1% |
| Freestone Grove Partners LP | 2,871,558 | $93.1m | 0.6% |
| Legal & General Group Plc | 2,652,752 | $86.0m | 0.0% |
| NORGES BANK | 2,542,640 | $82.5m | 0.0% |