| BlackRock, Inc. | 11,599,921 | $334.4m | 0.0% |
| FMR LLC | 7,004,280 | $201.9m | 0.0% |
| VANGUARD PORTFOLIO MANAGEMENT LLC | 5,019,465 | $144.7m | 0.0% |
| VANGUARD CAPITAL MANAGEMENT LLC | 3,210,723 | $92.6m | 0.0% |
| STATE STREET CORP | 3,022,859 | $87.1m | 0.0% |
| AMERIPRISE FINANCIAL INC | 2,763,514 | $79.7m | 0.0% |
| FORT WASHINGTON INVESTMENT ADVISORS INC /OH/ | 2,548,164 | $73.5m | 0.4% |
| GEODE CAPITAL MANAGEMENT, LLC | 1,969,208 | $56.8m | 0.0% |
| CITADEL ADVISORS LLC | 1,785,717 | $51.5m | 0.0% |
| DIMENSIONAL FUND ADVISORS LP | 1,688,670 | $48.7m | 0.0% |
| Soleus Capital Management, L.P. | 1,602,000 | $46.2m | 1.6% |
| MORGAN STANLEY | 1,535,897 | $44.3m | 0.0% |
| WELLINGTON MANAGEMENT GROUP LLP | 1,496,633 | $43.1m | 0.0% |
| DISCIPLINED GROWTH INVESTORS INC /MN | 1,181,632 | $34.1m | 0.6% |
| LOOMIS SAYLES & CO L P | 1,080,928 | $31.2m | 0.0% |
| BAILLIE GIFFORD & CO | 1,078,629 | $31.1m | 0.0% |
| JANE STREET GROUP, LLC | 1,063,363 | $30.7m | 0.0% |
| EASTERLY INVESTMENT PARTNERS LLC | 958,117 | $27.6m | 1.4% |
| CHARLES SCHWAB INVESTMENT MANAGEMENT INC | 954,065 | $27.5m | 0.0% |
| LSV ASSET MANAGEMENT | 895,636 | $25.8m | 0.0% |
| NORTHERN TRUST CORP | 802,885 | $23.1m | 0.0% |
| AQR CAPITAL MANAGEMENT LLC | 797,534 | $23.0m | 0.0% |
| AMERICAN CENTURY COMPANIES INC | 778,839 | $22.5m | 0.0% |
| Fideuram Asset Management (Ireland) dac | 904,062 | $18.4m | 0.3% |
| River Road Asset Management, LLC | 635,023 | $18.3m | 0.2% |