| BlackRock, Inc. | 14,525,539 | $115.0m | 0.0% |
| D. E. Shaw & Co., Inc. | 7,804,758 | $61.8m | 0.0% |
| VANGUARD CAPITAL MANAGEMENT LLC | 7,340,229 | $58.1m | 0.0% |
| STATE STREET CORP | 4,821,566 | $38.2m | 0.0% |
| GEODE CAPITAL MANAGEMENT, LLC | 4,718,183 | $37.4m | 0.0% |
| Nuveen, LLC | 4,385,141 | $34.7m | 0.0% |
| Rosalind Advisors, Inc. | 2,908,981 | $23.0m | 8.6% |
| Qube Research & Technologies Ltd | 2,893,749 | $22.9m | 0.0% |
| VANGUARD PORTFOLIO MANAGEMENT LLC | 2,626,208 | $20.8m | 0.0% |
| WELLINGTON MANAGEMENT GROUP LLP | 2,365,103 | $18.7m | 0.0% |
| MORGAN STANLEY | 2,337,096 | $18.5m | 0.0% |
| Legal & General Group Plc | 2,012,792 | $15.9m | 0.0% |
| ARMISTICE CAPITAL, LLC | 1,958,702 | $15.5m | 0.2% |
| TWO SIGMA INVESTMENTS, LP | 1,885,503 | $14.9m | 0.0% |
| Parkman Healthcare Partners LLC | 1,807,621 | $14.3m | 1.5% |
| ALGERT GLOBAL LLC | 1,742,942 | $13.8m | 0.2% |
| NORTHERN TRUST CORP | 1,597,749 | $12.7m | 0.0% |
| GOLDMAN SACHS GROUP INC | 1,594,072 | $12.6m | 0.0% |
| AQR CAPITAL MANAGEMENT LLC | 1,540,985 | $12.2m | 0.0% |
| CHARLES SCHWAB INVESTMENT MANAGEMENT INC | 1,492,367 | $11.8m | 0.0% |
| FEDERATED HERMES, INC. | 1,434,433 | $11.4m | 0.0% |
| BANK OF AMERICA CORP /DE/ | 1,397,050 | $11.1m | 0.0% |
| UBS Group AG | 1,300,913 | $10.3m | 0.0% |
| Ishara Investments LP | 1,230,000 | $9.7m | 7.2% |
| VANGUARD FIDUCIARY TRUST CO | 1,224,398 | $9.7m | 0.0% |