| FMR LLC | 8,814,946 | $13.0m | 0.0% |
| VANGUARD CAPITAL MANAGEMENT LLC | 2,829,927 | $4.2m | 0.0% |
| MARSHALL WACE, LLP | 2,049,802 | $3.0m | 0.0% |
| Aisling Capital Management LP | 2,048,757 | $3.0m | 0.6% |
| RENAISSANCE TECHNOLOGIES LLC | 1,455,474 | $2.1m | 0.0% |
| FIDEURAM - INTESA SANPAOLO PRIVATE BANKING S.P.A. | 723,176 | $1.1m | 0.0% |
| BlackRock, Inc. | 715,445 | $1.1m | 0.0% |
| GEODE CAPITAL MANAGEMENT, LLC | 708,854 | $1.0m | 0.0% |
| SUSQUEHANNA INTERNATIONAL GROUP, LLP | 612,735 | $900,720 | 0.0% |
| Mariner, LLC | 594,726 | $874,247 | 0.0% |
| JANE STREET GROUP, LLC | 458,289 | $673,685 | 0.0% |
| UBS Group AG | 444,728 | $653,750 | 0.0% |
| XTX Topco Ltd | 406,879 | $598,112 | 0.0% |
| TWO SIGMA INVESTMENTS, LP | 384,459 | $565,155 | 0.0% |
| MORGAN STANLEY | 367,021 | $539,521 | 0.0% |
| VANGUARD FIDUCIARY TRUST CO | 338,345 | $497,367 | 0.0% |
| MAI Capital Management | 289,100 | $424,977 | 0.0% |
| STATE STREET CORP | 257,315 | $378,253 | 0.0% |
| GSA CAPITAL PARTNERS LLP | 216,020 | $318,000 | 0.0% |
| LMR Partners LLP | 200,000 | $261,000 | 0.0% |
| NORTHERN TRUST CORP | 128,526 | $188,933 | 0.0% |
| Headlands Technologies LLC | 111,349 | $163,683 | 0.0% |
| Marex Group Ltd | 100,000 | $147,000 | 0.0% |
| GOLDMAN SACHS GROUP INC | 93,757 | $137,822 | 0.0% |
| BRIDGEWAY CAPITAL MANAGEMENT, LLC | 84,600 | $124,362 | 0.0% |