| JOHNSON & JOHNSON | 4,024,861 | $20.7m | 2.6% |
| NEA Management Company, LLC | 1,954,440 | $10.0m | 0.6% |
| BlackRock, Inc. | 1,245,459 | $6.4m | 0.0% |
| ROYAL BANK OF CANADA | 1,233,212 | $6.3m | 0.0% |
| GSK plc | 1,007,583 | $5.2m | 0.9% |
| VANGUARD CAPITAL MANAGEMENT LLC | 910,576 | $4.7m | 0.0% |
| SILVERCREST ASSET MANAGEMENT GROUP LLC | 878,109 | $4.5m | 0.0% |
| GEODE CAPITAL MANAGEMENT, LLC | 440,786 | $2.3m | 0.0% |
| PFM Health Sciences, LP | 369,572 | $1.9m | 0.2% |
| STATE STREET CORP | 366,352 | $1.9m | 0.0% |
| RENAISSANCE TECHNOLOGIES LLC | 230,000 | $1.2m | 0.0% |
| UBS Group AG | 224,233 | $1.2m | 0.0% |
| TUDOR INVESTMENT CORP ET AL | 205,684 | $1.1m | 0.0% |
| GOLDMAN SACHS GROUP INC | 149,509 | $768,476 | 0.0% |
| MORGAN STANLEY | 144,977 | $745,182 | 0.0% |
| Kestra Advisory Services, LLC | 132,400 | $680,536 | 0.0% |
| TWO SIGMA INVESTMENTS, LP | 132,398 | $680,526 | 0.0% |
| VANGUARD FIDUCIARY TRUST CO | 128,955 | $662,829 | 0.0% |
| DIMENSIONAL FUND ADVISORS LP | 127,971 | $659,866 | 0.0% |
| NORTHERN TRUST CORP | 124,767 | $641,302 | 0.0% |
| VANGUARD PORTFOLIO MANAGEMENT LLC | 105,915 | $544,403 | 0.0% |
| AQR CAPITAL MANAGEMENT LLC | 105,614 | $542,856 | 0.0% |
| Cresset Asset Management, LLC | 103,849 | $533,784 | 0.0% |
| BNP PARIBAS FINANCIAL MARKETS | 97,309 | $500,168 | 0.0% |
| Quantinno Capital Management LP | 82,333 | $423,192 | 0.0% |