| RA CAPITAL MANAGEMENT, L.P. | 2,387,744 | $859,349 | 0.0% |
| Balyasny Asset Management L.P. | 1,790,089 | $644,253 | 0.0% |
| VANGUARD CAPITAL MANAGEMENT LLC | 1,217,976 | $438,471 | 0.0% |
| RENAISSANCE TECHNOLOGIES LLC | 674,632 | $242,800 | 0.0% |
| Lynx1 Capital Management LP | 657,786 | $236,737 | 0.0% |
| SPHERA FUNDS MANAGEMENT LTD. | 626,810 | $225,589 | 0.0% |
| DC Funds, LP | 589,102 | $212,018 | 16.9% |
| Verdad Advisers, LP | 348,709 | $125,500 | 0.1% |
| GEODE CAPITAL MANAGEMENT, LLC | 335,815 | $120,895 | 0.0% |
| BANK OF AMERICA CORP /DE/ | 311,502 | $111,829 | 0.0% |
| XTX Topco Ltd | 271,478 | $97,705 | 0.0% |
| JANE STREET GROUP, LLC | 251,837 | $90,637 | 0.0% |
| UBS Group AG | 215,838 | $77,702 | 0.0% |
| VANGUARD FIDUCIARY TRUST CO | 157,726 | $56,781 | 0.0% |
| STATE STREET CORP | 119,168 | $42,889 | 0.0% |
| Squarepoint Ops LLC | 103,242 | $37,157 | 0.0% |
| BlackRock, Inc. | 101,573 | $36,556 | 0.0% |
| Rangeley Capital, LLC | 100,000 | $35,990 | 0.0% |
| NORTHERN TRUST CORP | 86,851 | $31,258 | 0.0% |
| Alyeska Investment Group, L.P. | 86,554 | $31,151 | 0.0% |
| MPM BIOIMPACT LLC | 80,142 | $28,851 | 0.0% |
| MILLENNIUM MANAGEMENT LLC | 62,055 | $22,334 | 0.0% |
| Virtu Financial LLC | 45,467 | $16,000 | 0.0% |
| GSA CAPITAL PARTNERS LLP | 27,146 | $10,000 | 0.0% |
| TWO SIGMA INVESTMENTS, LP | 27,300 | $9,825 | 0.0% |