| Bain Capital Investors LLC | 26,255,581 | $578.4m | 12.0% |
| Bain Capital Life Sciences Investors, LLC | 22,583,268 | $497.5m | 29.6% |
| RTW INVESTMENTS, LP | 10,776,820 | $237.4m | 2.0% |
| CANADA PENSION PLAN INVESTMENT BOARD | 7,304,688 | $160.9m | 0.1% |
| Atlas Venture Life Science Advisors, LLC | 5,171,282 | $113.9m | 12.9% |
| FMR LLC | 3,970,865 | $87.5m | 0.0% |
| BlackRock, Inc. | 3,928,604 | $86.5m | 0.0% |
| PRICE T ROWE ASSOCIATES INC /MD/ | 3,534,410 | $77.9m | 0.0% |
| CITADEL ADVISORS LLC | 3,240,787 | $71.4m | 0.0% |
| ADAGE CAPITAL PARTNERS GP, L.L.C. | 3,208,286 | $70.7m | 0.1% |
| WELLINGTON MANAGEMENT GROUP LLP | 2,919,110 | $64.3m | 0.0% |
| Royalty Pharma Sub-Manager, LLC | 2,455,357 | $54.1m | 22.4% |
| Siren, L.L.C. | 2,214,286 | $48.8m | 1.0% |
| VANGUARD CAPITAL MANAGEMENT LLC | 1,693,958 | $37.3m | 0.0% |
| VANGUARD PORTFOLIO MANAGEMENT LLC | 1,652,507 | $36.4m | 0.0% |
| GEODE CAPITAL MANAGEMENT, LLC | 1,133,115 | $25.0m | 0.0% |
| Frazier Life Sciences Management, L.P. | 1,100,000 | $24.2m | 0.5% |
| FARALLON CAPITAL MANAGEMENT, L.L.C. | 1,100,000 | $24.2m | 0.1% |
| Trails Edge Capital Partners, LP | 984,786 | $21.7m | 3.4% |
| UBS Group AG | 972,683 | $21.4m | 0.0% |
| Jupiter Topco LLC | 970,857 | $21.3m | 0.0% |
| AMERIPRISE FINANCIAL INC | 821,331 | $18.1m | 0.0% |
| Deep Track Capital, LP | 700,000 | $15.4m | 0.2% |
| EVENTIDE ASSET MANAGEMENT, LLC | 616,720 | $13.6m | 0.2% |
| Vestal Point Capital, LP | 575,000 | $12.7m | 0.3% |