| BlackRock, Inc. | 1,939,818 | $75.9m | 0.0% |
| Soleus Capital Management, L.P. | 1,843,504 | $72.1m | 2.5% |
| ARMISTICE CAPITAL, LLC | 1,672,000 | $65.4m | 0.8% |
| STATE STREET CORP | 1,039,994 | $40.7m | 0.0% |
| VANGUARD CAPITAL MANAGEMENT LLC | 785,107 | $30.7m | 0.0% |
| AMERICAN CENTURY COMPANIES INC | 741,718 | $29.0m | 0.0% |
| LSV ASSET MANAGEMENT | 721,666 | $28.2m | 0.1% |
| ACADIAN ASSET MANAGEMENT LLC | 591,686 | $23.1m | 0.0% |
| D. E. Shaw & Co., Inc. | 542,539 | $21.2m | 0.0% |
| GEODE CAPITAL MANAGEMENT, LLC | 483,175 | $18.9m | 0.0% |
| MARSHALL WACE, LLP | 367,393 | $14.4m | 0.0% |
| CM Management, LLC | 250,000 | $9.8m | 6.2% |
| VANGUARD PORTFOLIO MANAGEMENT LLC | 233,728 | $9.1m | 0.0% |
| DIMENSIONAL FUND ADVISORS LP | 227,951 | $8.9m | 0.0% |
| GOLDMAN SACHS GROUP INC | 226,780 | $8.9m | 0.0% |
| TWO SIGMA INVESTMENTS, LP | 207,578 | $8.1m | 0.0% |
| NOMURA ASSET MANAGEMENT INTERNATIONAL INC. | 195,000 | $7.6m | 0.0% |
| MORGAN STANLEY | 186,049 | $7.3m | 0.0% |
| CHARLES SCHWAB INVESTMENT MANAGEMENT INC | 154,627 | $6.0m | 0.0% |
| NORTHERN TRUST CORP | 146,381 | $5.7m | 0.0% |
| RENAISSANCE TECHNOLOGIES LLC | 145,846 | $5.7m | 0.0% |
| O'SHAUGHNESSY ASSET MANAGEMENT, LLC | 131,177 | $5.1m | 0.0% |
| AQR CAPITAL MANAGEMENT LLC | 124,801 | $4.9m | 0.0% |
| BRIDGEWAY CAPITAL MANAGEMENT, LLC | 124,184 | $4.9m | 0.1% |
| Nuveen, LLC | 123,961 | $4.8m | 0.0% |